The most widely applied tactic for hypoxic tumor cell detection continues to be the development of nitroimidazole hypoxic markers. Nitroheterocyclic brokers, originally developed as radiation sensitizers, comprise an RNO2 aspect chain that results in being speedily reduced from the absence of oxygen30, 31 and binds to cellular adducts.68suggest tha
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Despite the troubles related with analyzing the oxygenation status of tumors, it is evident from reports employing a range of methodologies that hypoxia exists in human tumors and that it could affect radiation response.forty seven Results have shown hypoxia to have a substantial impact on equally regional tumor control and overall survival in a va
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